Détails bibliographiques
| Autres auteurs : |
Giaccone Giuseppe,
Pinedo H. M. |
| Format : |
Livre |
| Langue : |
anglais |
| Titre complet : |
Drug resistance in the treatment of cancer / edited by Herbert M. Pinedo and Giuseppe Giaccone |
| Publié : |
Cambridge, U.K., New York :
Cambridge University Press
, c1998
|
| Description matérielle : |
xvi, 323 p. |
| Collection : |
Cancer, clinical science in practice
|
| Contenu : |
Resistance mechanisms to antimetabolites. Resistance to antitumor alkylating agents and cisplatin. The MDR genes. Topoisomerase genes and resistance to topoisomerase inhibitors. Genes that modulate apoptosis: major determinatns of drug resistance. Clinical implications of drug resistance. The reversal of multidrug resistance. Effect of dose and schedule on chemotherapeutic drug resistance. Circumvention of drug resistance by high-dose chemotherapy in solid tumors. Enhancing drug effectiveness by gene transfer |
| Sujets : |
|
Nantilus
