Protein engineering of antibody molecules for prophylactic and therapeutic applications in man

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Détails bibliographiques
Auteur principal : Clark Mike (Éditeur scientifique)
Format : Livre
Langue : anglais
Titre complet : Protein engineering of antibody molecules for prophylactic and therapeutic applications in man / edited by Mike Clark
Édition : 1st edition
Publié : Nottingham : Academic Titles , C 1993
Description matérielle : 1 vol. (XI-182 p.)
Sujets :
  • Derivation of recombinant antibodies
  • Reshaping antibodies for therapy / E.G. Routledge, S.D. Gorman, M. Clark
  • Building an in vitro immune system: human antibodies from phage display libraries / A. Griffiths, H.R. Hoogenboom
  • Human antibodies from combinatorial libraries / D.R. Burton, C.F. Barbas III
  • Antibody effector functions
  • Effector functions of matched sels of recombinant human IgG subclass antibodies / J. Greenwood, M. Clark
  • Complement activation and Fc receptor binding by IgG / S.L. Morrison, S.M. Canfield, M. Tao
  • Molecular characterisation of IgG antibody effector sites / R. Jefferis, J. Lund
  • Chemically engineered chimeric and multi-Fab antibodies / G.T. Stevenson, M.J. Glennie, K.S. Kan
  • Therapeutic applications
  • Engineering monoclonal antibody B72.3 for cancer therapy / J.R. Adair [and others]
  • Humanised antibodies to the IL-2 receptor / C. Queen, W.P. Schneider, T.A. Waldmann
  • Clinical studies with murine and chimeric 17-1A in colorectal cancer patients / A.F. LoBuglio, M.B. Khazaeli