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Bioactive Heterocycles III
Bioactive Heterocycles III provides readers with a comprehensive overview of the most recent breakthroughs in the ?eld of heterocycles. This volume contains 8 chapters written by experts in their respective ?elds from all over the world. The chapters summarize years of extensive research in each are...
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| Auteur principal : | |
|---|---|
| Autres auteurs : | |
| Format : | Livre |
| Langue : | anglais |
| Titre complet : | Bioactive Heterocycles III / edited by Mahmud Tareq Hassan Khan. |
| Édition : | 1st ed. 2007. |
| Publié : |
Berlin, Heidelberg :
Springer Berlin Heidelberg
, [20..] Cham : Imprint: Springer Springer Nature |
| Collection : | Topics in heterocyclic chemistry (Internet) ; 9 |
| Titre de l'ensemble : | Topics in Heterocyclic Chemistry vol. 9 |
| Accès en ligne : |
Accès Nantes Université
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| Condition d'utilisation et de reproduction : | Conditions particulières de réutilisation pour les bénéficiaires des licences nationales : https://www.licencesnationales.fr/springer-nature-ebooks-contrat-licence-ln-2017 |
| Contenu : | Chemistry, Biosynthesis and Biological Activity of Artemisinin and Related Natural Peroxides. Sugar-derived Heterocycles and Their Precursors as Inhibitors Against Glycogen Phosphorylases (GP). Cytotoxicity of Heterocyclic Compounds against Various Cancer Cells: A Quantitative Structure Activity Relationship Study. Synthesis, Reactivity and Biological Activity of Benzimidazoles. Heterocyclic Compounds Against the Enzyme Tyrosinase Essential for Melanin Production: Biochemical Features of Inhibition. Xanthones in Hypericum: Synthesis and Biological Activities. Chemistry of Biologically Active Isothiazoles. Structure and Biological Activity of Furocoumarins. Erratum to Xanthones in Hypericum: Synthesis and Biological Activities |
| Sujets : | |
| Documents associés : | Autre format:
Bioactive heterocycles III |
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| 327 | 1 | |a Chemistry, Biosynthesis and Biological Activity of Artemisinin and Related Natural Peroxides |a Sugar-derived Heterocycles and Their Precursors as Inhibitors Against Glycogen Phosphorylases (GP) |a Cytotoxicity of Heterocyclic Compounds against Various Cancer Cells: A Quantitative Structure Activity Relationship Study |a Synthesis, Reactivity and Biological Activity of Benzimidazoles |a Heterocyclic Compounds Against the Enzyme Tyrosinase Essential for Melanin Production: Biochemical Features of Inhibition |a Xanthones in Hypericum: Synthesis and Biological Activities |a Chemistry of Biologically Active Isothiazoles |a Structure and Biological Activity of Furocoumarins |a Erratum to Xanthones in Hypericum: Synthesis and Biological Activities | |
| 330 | |a Bioactive Heterocycles III provides readers with a comprehensive overview of the most recent breakthroughs in the ?eld of heterocycles. This volume contains 8 chapters written by experts in their respective ?elds from all over the world. The chapters summarize years of extensive research in each area, andprovideinsightinthenewthemesofnaturalproductresearch.Manyofthe contributors illustrate their laboratory experiences. It s obvious that readers will gain exciting and essential information fromthe volume. In the ?rst chapter, Kayser et al. describe the chemistry, biosynthesis and biological activities of artemisinin, one of the most promising antimalarial molecules, and its related natural peroxides. They present new strategies of producing artemisinin that utilize fascinating technologies. as Additionally, thepharmacokineticpro?leandthedevelopmentofnewdrugdeliverysystems onPlasmodium infected erythrocytesare presented . Khan describes some aspects of sugar-derived heterocycles and their p- cursors which are utilized as the inhibitors against glycogen phosphorylases (GPs), and are responsible for the release of mono-glucose from poly-glucose (glycogen) in the second chapter. The inhibitors of GP could help to stop or slowdownglycogenolysisaswellasglucoseproduction.Ultimately, thewhole processwill result in the recovery fromdiabetes of NIDDMpatients. In his contribution, Verma studies quantitative structure-activityrelati- ship (QSAR) and proposes several interesting QSAR models of heterocyclic molecules having cytotoxicactivities against different cancer cell lines, which couldin turn clarify the chemical-biologicalinteractions ofsuch compounds. Alamgir et al., in the fourth chapter, review the recent progress of the synthesis, reactivity and biological activities of benzimidazoles. Additionally, they describe several new techniques and procedures for the synthesis of the same scaffold. Inthe?fthchapter,KhanreviewstheessentialroleoftheenzymeTyrosinase in human melanin production, covering various related clinical problems | ||
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